Nitib Ibrutinib 140mg Capsules 30's

The Nitib 140mg capsule consists of the active ingredient Ibrutinib. It is indicated to treat blood cancers such as mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (CLL), Waldenstrom’s macroglobulinemia, and Marginal zone lymphoma (MZL). These are cancers of the white blood cells called lymphocytes that are part of the immune system. They differ from each other by the location where cancer occurs, the type of lymphocytes affected, and certain other factors.

The Nitib 140 mg capsule is also used to treat chronic graft versus host disease (cGvHD) after the failure of systemic therapy. During allogeneic stem cell transplantation, the patient receives stem cells from the donor. GvHD occurs when donor cells attack the patient's cells as foreign. Before taking the Nitib 140 mg Capsule, you need to talk with your physician if you have bleeding problems, infection, liver problems, heart problems, or intolerance to some sugars. This medication is not recommended for adolescents and children. 

It is vital to let the physician know if you have recently had or are about to have any surgical procedure. Your physician may stop the Nitib 140 mg capsule for any planned surgical or medical procedure. Use effective birth control during the treatment and for at least one month after the final dose. Avoid having grapefruit or oranges in any form during this treatment; they may raise the amount of drug in the blood. Drink plenty of fluid to prevent dehydration. Inform your physician if you have diarrhea that does not go away.

• Mantle cell lymphoma
• Chronic lymphocytic leukemia (blood cancer)
• Small lymphocytic lymphoma
• Waldenstrom’s macroglobulinemia
• Chronic graft vs. host disease after failure of systemic therapy

The mechanism of action of Nitib 140 mg involves blocking a specific protein called Bruton's tyrosine kinase (BTK) which plays a key role in the survival and growth of cancer cells. By inhibiting BTK, Nitib 140 mg prevents the cancer cells from receiving the signals they need to grow and divide, leading to their eventual death.

Consume this medicine at the same time each day. While taking Nitib 140 mg, do not consume grapefruit or oranges in any form during the treatment. Drink plenty of fluid to prevent dehydration.

Serious:

• Bleeding problems
• Infections
• Decrease in blood cell counts
• Heart problems
• High BP
• Secondary cancer
• Tumor lysis syndrome
• Severe allergic reactions

Common:

• Nausea, vomiting, diarrhea
• Tiredness
• Muscle and bone pain
• Rash and bruising
• Mouth sores
• Pneumonia
• Fever, chills
• Breathlessness
• Constipation
• Dizziness
• Body pain
• Swollen ankles and feet
• Increased creatinine levels in blood
• Heavier periods and blood in urine
• Blurred vision
• Weakness and numbness

Inform your healthcare professional about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interacting with Nitib 140 mg may reduce effectiveness by causing undesirable side effects. 

Store the capsules in the original packaging at room temperature (20-25°C).

• Contact your doctor right away if you experience bleeding, infection, shortness of breath, or chest discomfort.
• Inform your doctor if you have a history of heart failure or hepatitis infection before starting treatment.
• Avoid taking this medicine before or after surgery, as it may delay wound healing.
• Use effective contraception during treatment and for at least one month after the last dose, as advised by your healthcare provider.